Enrotril should be reserved for serious infections. It is the treatment of choice for Salmonella infections and plays a major role in the successful elimination of this disease. Enrotril is the first choice medicine for important seriously ill birds where the cause of the illness is uncertain. The unnecessary use of Enrotril increases the likelihood of birds developing a resistance to this antibiotic. Such resistance may lead to a loss of effectiveness when this important medicine is required to treat a more serious problem.